What remains is for the MAHA men to upgrade their understanding of arachidonic acid, endocannabinoid system, and eicosanoid issues. For example, "Eicosanoids are major players in the pathogenesis of several common diseases, with either overproduction or imbalance (e.g. between thromboxanes and prostacyclins) often leading to worsening of disease symptoms. Both the total rate of eicosanoid production and the balance between eicosanoids with opposite effects are strongly dependent on dietary factors, such as the daily intakes of various eicosanoid precursor fatty acids, and also on the intakes of several antioxidant nutrients including selenium and sulphur amino acids. Even though the underlying biochemical mechanisms have been thoroughly studied for more than 30 years, neither the agricultural sector nor medical practitioners have shown much interest in making practical use of the abundant high-quality research data now available." https://lipidworld.biomedcentral.com/articles/10.1186/1476-511X-10-16
Endocannabinoids: "The white paper, “Addressing the Omega-6 and Omega-3 Imbalance in the U.S. Food Supply”, highlights the growing public health crisis driven by excessive omega-6 fatty acid consumption and widespread omega-3 deficiencies—an imbalance fueling America’s chronic disease epidemic...Among the white paper’s most urgent findings are that the omega-6 heavy American diet disrupts immune function, increases inflammation, and elevates disease risk. Military readiness and cognitive resilience are threatened by poor fatty acid balance. The imbalance overstimulates the body’s endocannabinoid system—worsening obesity, inflammation, and mental health disorders, especially in youth." https://www.kxan.com/business/press-releases/ein-presswire/795302194/experts-sound-alarm-on-dangerous-omega-6-and-omega-3-imbalance-in-u-s-food-supply/
What remains is for the MAHA men to upgrade their understanding of arachidonic acid, endocannabinoid system, and eicosanoid issues. For example, "Eicosanoids are major players in the pathogenesis of several common diseases, with either overproduction or imbalance (e.g. between thromboxanes and prostacyclins) often leading to worsening of disease symptoms. Both the total rate of eicosanoid production and the balance between eicosanoids with opposite effects are strongly dependent on dietary factors, such as the daily intakes of various eicosanoid precursor fatty acids, and also on the intakes of several antioxidant nutrients including selenium and sulphur amino acids. Even though the underlying biochemical mechanisms have been thoroughly studied for more than 30 years, neither the agricultural sector nor medical practitioners have shown much interest in making practical use of the abundant high-quality research data now available." https://lipidworld.biomedcentral.com/articles/10.1186/1476-511X-10-16
Endocannabinoids: "The white paper, “Addressing the Omega-6 and Omega-3 Imbalance in the U.S. Food Supply”, highlights the growing public health crisis driven by excessive omega-6 fatty acid consumption and widespread omega-3 deficiencies—an imbalance fueling America’s chronic disease epidemic...Among the white paper’s most urgent findings are that the omega-6 heavy American diet disrupts immune function, increases inflammation, and elevates disease risk. Military readiness and cognitive resilience are threatened by poor fatty acid balance. The imbalance overstimulates the body’s endocannabinoid system—worsening obesity, inflammation, and mental health disorders, especially in youth." https://www.kxan.com/business/press-releases/ein-presswire/795302194/experts-sound-alarm-on-dangerous-omega-6-and-omega-3-imbalance-in-u-s-food-supply/
MAHA Commission members have yet to address the excess of arachidonic acid in the food supply. https://journals.biologists.com/jeb/article/224/8/jeb232538/256572/The-under-appreciated-fats-of-life-the-two-types